Mitomycin C is part of a family of azidine natural products. It is a DNA crosslinking and damaging agent, making it a useful antibiotic and antitumor compound. When crosslinking, Mitomycin C displays absolute specificity and high efficiency for the CpG sequence. Mammalian Cells treated with Mitomycin C (0.4 mg/mL for 5 min) can undergo apoptosis through upregulation of Bad, Fas, FasL and phosphorylated p53 along with activation of caspase-3, caspase-8, and caspase-9 activating both the intrinsic and extrinsic pathway for apoptosis.

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文件类别	产品名称	产品号#	语言	下载
产品说明书	Mitomycin C	AAPRa-0820	English	点击下载
技术手册	Mitomycin C	AAPRa-0820	中文简体	点击下载
安全说明书	Mitomycin C	AAPRa-0820	中文简体	点击下载